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Molecular Motors in Bionanotechnology, by Keith Firman, James Youell
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Biological molecular motors provide most cells with the dynamic systems required for their day-to-day existence. Examples occur in even the simplest organism (e.g. a bacteria virus), and the range of tasks that they carry out is vast. Over the last few years, there has been a large increase in the study of these motors, and it is becoming apparent that many motors will find uses in either bionanotechnology or synthetic biology.
Molecular Motors in Bionanotechnology describes a wide range of molecular motors, ranging from chemical motors to biological motors, in a manner that updates, or reviews, both classification of the type of motor and the grouping into families. Many techniques have evolved to study and characterise molecular motors at the single-molecule level (e.g. use of molecular tweezer devices for single-molecule studies). The text introduces the reader to the concepts and benefits of these techniques. In addition, it looks at the structural information and how this helps understand function and, finally, how some of these motors are being used or may be used in the future as part of a synthetic biology approach to building devices and sensors.
- Sales Rank: #7125243 in Books
- Brand: Brand: Pan Stanford Publishing
- Published on: 2013-03-18
- Original language: English
- Number of items: 1
- Dimensions: 9.10" h x .60" w x 6.10" l, .0 pounds
- Binding: Hardcover
- 212 pages
- Used Book in Good Condition
About the Author
James Youell has been working as a research fellow since 2004 at the University of Portsmouth on the design of a high-throughput single-molecule drug development tool utilising molecular motors. Through the development of this system, he has worked alongside a pan European research team, incorporating cutting-edge experimental tools, to build the various biological and synthetic components required. Dr Youell has published a number of papers on the development of such synthetic biology devices and given invited seminars on the subject.
Keith Firman is now retired from the University of Portsmouth, where he was reader in Molecular Biotechnology. He investigated the properties of type I restriction-modification systems. This led to the coordination of three consecutive European grants worth, in total, in excess of €4,500,000 to develop an electronic device for biosensing using single-molecule molecular motors. Dr Firman has published more than 50 papers and was also invited to participate in a number of international road-mapping exercises in nanotechnology.
Most helpful customer reviews
0 of 0 people found the following review helpful.
Good but too brief
By Jerry Kurjian
Overall Molecular Motors in Bionanotechnology was an interesting read. The writing is clear and engaging; the volume's illustrations are numerous and detailed, though see below. This would be a great book if it were expanded in a later edition. Disappointingly, however, this volume is very short, being just shy of 200 pages, of which only 130 pages are actual text, most of the rest being references. Moreover, there are times when the authors get off track and go into detail about information that, for such a slim volume whose focus is molecular motors, doesn't seem relevant. For example, some 14 pages are spent listing the more than 20 subclasses of myosin, but these proteins are never described as being distinct molecular motors. Similarly, members of the kinesin family are enumerated over several pages without their being described as significantly different motors. The illustrations in the volume are very engaging, though at times the detail is difficult to see. It looks like they may have been shrunk to fit the text's smallish pages. The captions of the illustrations, however, were very disappointing, having little or no information about what is being illustrated. All in all, I wished the authors had provided more of the kinds of information that is fascinating in the volume - more types and variations of molecular motors, more about their mechanisms, about how they are assembled, and how they can be used ... and less extraneous information that I can read elsewhere.
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